Bone cancer

Scientists Have Discovered A Molecule That Blocks The Work Of Ewing Sarcoma Oncogene

By: Kiryl Hil

Bone cancer is primary or secondary (metastatic) malignant tumor that affects skeletal system of the organism. Primary malignant tumors of bone represented by sarcoma, i.e. connective origin tumors, they arise directly in the bones or joints.
Metastatic cancer develops of malignant tumor cells, which were formed in other cancer-affected organs and tissues and gotten thus in bones or joints, usually by hematogenic way (via blood). There are many types of bone cancer; one of the rarest and most dangerous is Ewing sarcoma. An interesting and rather hopeful research was conducted in the USA.

Researchers from the Georgetown University Medical Center discovered a small molecule, which, they said, blocks the effects of oncogene responsible for the development of Ewing sarcoma.

Ewing sarcoma - this is a rare type of cancer of different types occurring in children and young people. If further research in this area confirm this discovery will be the first drug targeting the molecular mechanism of action for the treatment of this pathology.
The unique operating principle of this molecule based on the so-called protein-protein interactions. Based on this, it is possible to develop effective molecular-targeted therapy, said principal investigator Jeffrey Toretsky, MD, pediatric oncology and a researcher from Georgetown University's Lombardi Comprehensive Cancer Center.

Ewing sarcoma occurs in an exchange of DNA between two chromosomes (a process called translocation). The new gene, known as EWS-FLI1, is formed when the EWS gene on 22 chromosome combined with the FLI1, located on chromosome 11. It is that protein that responsible for the development of sarcoma.

Toretsky and his colleagues were the first who was able to separate these 2 genes. They were trying to determine whether it's possible the binding of EWS-FLI1 with other cell proteins. Indeed, the protein formed by the merger of two genes linked with other protein (RHA), resulting in the formation of complex that is capable to control transcription.

Using laboratory techniques found that the RHA and EWS-FLI1 played important roles in the development of cancer. Then the scientists tried to identify a specific locus, which is to be attached to EWS-FLI1 RHA.

Additional actions were aimed at finding molecules that can prevent the connection of these two proteins. Try about 3000 samples of the Georgetown National Cancer Institute, USA, the scientists managed to find one that is tightly binds the desired protein.

For the amazing study Toretsky was awarded in the amount of $ 750,000, which he intends to spend on further development of a new treatment of Ewing sarcoma.

Author Resource:-> Information about bone cancer including bone cancer symptoms, Definition of bone cancer and treatment of primary bone cancer. Visit: http://bonecancersymptoms.org/

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Obesity And Liver Cancer

Obesity And Liver Cancer, Is There A Link?

By: Kiryl Hil

Primary liver cancer is not available in Western countries and is often recorded in Africa and parts of Asia.

In developed countries, primary liver cancer mainly affects middle-aged and elderly people, and 2 times more common in men, then in women. The majority of patients with hematomas are usually already having liver cirrhosis, which is characterized by nodal regeneration of hepatocytes as a result of many years alcohol abuse.

Sometimes hepatomas occur as a complication of hepatitis, acquired during chronic. Both of them is quite common, but as a complication of liver cancer is rare. In Africa and Asia, a primary liver cancer is much broader and may meet on the third and fourth lives a dozen people who have no liver damage as a result of alcohol abuse.

It is believed that the reason for this could be the impact of aflatoxin - the exchange of products of fungi found in grain and beer. There was also a clear link with liver cancer hepatitis. Many bile duct cancers are probably the consequence of liver fluke invasion.

Besides, some people think that there is a link between obesity and liver cancer. A group of researchers from the Johns Hopkins Medical School, the University of California, Los Angeles (USA) argue that obesity is an even stronger risk factor for liver cancer than cirrhosis. That is disappointing, scientists have concluded, after reviewing the results of their multicentered, randomized, and in some cases, pathological studies.

At the same time, assessed the presence and degree of liver fat transformation accompanying obesity in more than 80% of cases. It was found that more than half of patients (at 26), had a higher body mass index, while 18 had signs of fat hepatitis. After analyzing the delayed results in 10 years from the start of the project, the scientists concluded that the trend would continue. Moreover, with age the number of people with excess weight has been growing steadily, and compensatory ability of the liver are reduced, which further underlines the impartial connect.

As an output, and an explanation of the authors propose the following concept: the resulting fatty degeneration of liver are regarded as precancerous conditions. At the same time there are rapid proliferation, i.e. growth and development of cells of the liver, and inhibition of programmed death, or apoptosis - the process of protecting the rule of tumors. These processes are likely to self-stimulate neogenesis, i.e. the growth of tumor cells.

Author Resource:-> Site "Liver Cancer Symptoms" answers on such questions like: what are the symptoms of liver cancer, what is liver cancer and how frequent is liver cancer. Visit: http://livercancersymptoms.org/

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Bowel Cancer

Marijuana May Lead To Bowel Cancer

By: Kiryl Hil

Bowel cancer - is a rare tumor but rather insidious. It affects young men between 20 and 40 years old and sometimes very quickly gives metastases. Own health is in the full sense in the hands of men, because the bowel cancer can be detect only by himself or his attentive woman.

The peak of incidence is in 32 years (for other tumors is 68 years old), and after forty years, the risk of falling ill such disease significantly reduced. The most common bowel cancer suffer men from Switzerland (12-14 people per 100 thousand men), and least likely - African-Americans and Chinese. In recent years, the frequency of disease increases.


Bowel cancer occurs infrequently and mainly in children (about 30% of all tumors of childhood), and young people. In general, men's bowel cancer is about 1% of all malignant neoplasm. The main factors contributing to bowl cancer development are: chryptorchidism, bowl's trauma, Klyaynfelter syndrome, microwave, X-ray and gamma-radiation, infertility.


Local spread of bowl spread seen in increase of testicle size, germination in other departments (appendage, bowl's shell).

As it was said before, there are many causes of bowel cancer. But not long ago, researches found one more reason due to witch occurs the cancer of bowels.

Frequent or prolonged use of marijuana may increase the risk of developing the bowel cancer in men, say U.S. researchers Employees Fred Hutchinson Cancer Research Center in Seattle for the first time investigated the specific relationship between marijuana use and disease.

According to the results published in the journal Cancer interviewing 369 men aged 18 to 44 years diagnosed with cancer, who regularly smoked marijuana, the risk of falling ill is doubled as compared with those who never used this "easy" drugs.

Simply marijuana smoking is 70% extra risk, while smokers experienced this figure rises by half compared with those who never used the "grass". In addition, marijuana may be associated with the most aggressive type of tumor. This, in particular, nonseminoma - fastest growing form of bowel cancer, which accounts for approximately 40% of all cases and affects mainly young people.

Bowel cancer is one of the most frequent types of cancer in younger men. Each year in the UK occur approximately 2000 new cases. The level of incidence in Europe and North America are much higher than in some other parts of the world, and increases without apparent reason. The major risk factors include previous injury of testicles, heredity, undescended testicles in childhood.

Author Resource:-> Find more about symptoms of bowel cancer, treatment options for bowel cancer and what causes bowel cancer online on "Bowel Cancer Symptoms" site.

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Prostate Cancer: Symptoms

Prostate Cancer: Symptoms, Risk Factors and Treatments

By: Joseph Mix

Prostate cancer means that cancer cells form in the tissues of the prostate, the walnut-sized gland that surrounds the urethra in men. It is the most common cancer in American men after skin cancer. Prostate cancer tends to grow slowly compared with most other cancers and may require 10, 20, or 30 years before the tumor gets big enough to cause symptoms. Eventually, cancer cells may metastasize (spread) throughout the body.


By the time symptoms appear, the cancer may be more advanced. By age 50, very few men have symptoms of prostate cancer, yet some precancerous or cancerous cells are present. More than half of all American men have some cancer in their prostate glands by the age of 80. Most of these cancers never pose a problem. They either give no signs or symptoms or never become a serious threat to health. A much smaller percentage of men are actually treated for prostate cancer. Many men with prostate cancer do not die from this disease.


Prostate cancer can sit quietly for years, and most men with the disease have no obvious symptoms. When symptoms finally appear, they may be similar to the symptoms of BPH:

• Trouble passing urine
• Frequent urge to pass urine
• Weak or interrupted stream
• Pain or burning
• Nagging pain in the back, hips, or pelvis

Prostate cancer can spread to the lymph nodes of the pelvis, or it may spread throughout the body, often to the bones. Bone pain, especially in the back, can be a symptom. The risk factors for prostate cancer are:

• Age -- being 50 or older increases the risk of prostate cancer
• Race -- African-American men have the highest risk; Asian-American men have the lowest; Caucasian, Hispanic and Native-American men are in between.
• Family History -- The risk is two to three times higher in men whose fathers or brothers have had the disease; slightly higher for men whose mothers and sisters have had breast cancer
• Diet -- higher in men who eat high fat diets with few fruits and vegetables

Early detection is crucial to successful treatment. Men over the age of 50 should have annual prostate exams by a qualified physician who may perform one or more of the following:

• Health history and current symptoms
• Digital rectal exam (DRE) -- The DRE is the standard way to check the prostate. With a gloved and lubricated finger, the doctor feels the prostate from the rectum. The test lasts about 10 to 15 seconds. This exam checks for size, firmness, and texture of the prostate; any hard areas, lumps, or growth spreading beyond the prostate; and pain in the prostate.
• Prostate Specific Antigen Test (PSA) -- PSA is a protein made by normal cells and prostate cancer cells. It is found in the blood and can be measured with a blood test. PSA levels can rise if a man has prostate cancer, but a high PSA is not proof of cancer. PSA levels go up with age. African-American men tend to have higher PSA levels. Doctors often use a score of 4 (nanograms) or higher to determine that further tests are necessary.
• Prostate Biopsy -- If cancer is suspected, a biopsy may be indicated. Usually performed by a urologist, small tissue samples are taken directly from the prostate and examined under a microscope. Most men who have biopsies after routine exams do not have cancer, but it is best to check if cancer is suspected.

Treatment options for prostate cancer include:

• Surgery
• Radiation, including implantable radon seeds
• Chemotherapy
• A combination of the above

Author Resource:-> Dr. Joseph Mix a Professor of Health Sciences at Liberty University, a member of the American College of Nutrition, and a Certified Nutrition Specialist has conducted original research in the area of herbal medicine. Go to " target="_blank">http://www.NaturalHealthMix.com for more information.

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Alternative Cancer Treatment

The Most Effective, Alternative Cancer Treatment Revealled

By: Ranju Kumar

In 1971, President Richard M. Nixon declared war on cancer in the USA. All the billions spent on cancer research have only gone into finding new ways of chemotherapy, radiation and surgery. Since then, inexpensive, time tested, natural therapies which were used successfully for decades around the world remain ignored by the conventional medical system.

A fact is that, behind the scenes, millions of people worldwide have successfully treated cancer using low cost, natural, alternative cancer treatments since 1920.
The cancer may start with just one or a few cells somewhere in the body that undergo a change and become malignant, or cancerous. The cells divide and reproduce themselves, and the cancer grows. Most cancers arise on the surface of a tissue, such as the skin, the lining of the uterus, mouth, stomach, bowel, bladder, or bronchial tube in the lung, or inside a duct in the breast, prostate gland, or other site.

Eventually, they grow from a microscopic clump to a visible mass, then begin to invade underlying tissues. As long as the cells remain in one mass, however, the cancer is localized.
At some later phase, in a process called metastasis, some of the cancer cells split off and are swept into the lymph channels or bloodstream to other parts of the body. They may be captured for a while in a nearby lymph node (a stage called regional involvement), but unless the disease is arrested, it will rapidly invade the rest of the body, with death the almost certain result.

Some cancers grow with malevolent rapidity; some are dormant by comparison. Some respond to various therapies, such as radiation therapy; others do not. About half of the known types of cancer are incurable at any stage. Of the remaining half, it is obviously imperative to diagnose and treat them as early as possible.

If you are seriously considering alternative cancer treatment therapies, you should not rush yourself into any kind of medicine. You should take your time because there are a lot of information that you must know and mistakes you must avoid.

There are a lot of natural treatments available but you must remember that they only work on a minority of people who use it correctly. It also depends on the body chemistry of the patient. There isn't a best treatment for a certain type or stage of cancer.

Conventional doctors use alternative cancer therapies. They just put themselves at legal and professional risk unless they use chemotherapy, radiation, surgery and expensive drugs. The judgment of doctors as to what is best for you can never be imposed unless the medical politics at the federal level and state level approve of it.

Unfortunately, FDA only promotes pharmaceutical drugs and has a long record of not approving anything alternative. No matter how well alternative treatments work, MDs can never use these because they don't want any problems that can damage their careers.

The success of these so called alternative cancer treatments is either overstated by the community for alternative cancer treatment, or understated by the traditional ones. But if you really want to treat your cancer through alternative therapies, doctors around the world have found these 6 basic kinds of natural alternative cancer treatments that should be used together:

1. Whole Body Detoxification
2. Nutrition & Oxygenation
3. Immune system building
4. Enzymatic therapy
5. Mental and emotional counseling
6. Non-toxic, natural chemotherapies

These are some wonderful therapies that can help people get rid of some serious diseases.



Author Resource:-> The website 1MinuteCure.com reveals the information on how a simple formula has been scientifically proven to cure Cancer and virtually any disease. Visit the website for more details http://www.1minutecure.com/.

Article From Champion Articles

Aloe Vera/Honey/whisky Treatment against Cancer

Ingredients

A) 300 grams of Aloe Vera(fresh pulp of the leaf)^*B) 500 grams of bee honey (pure honey)
C) 4 - 5 tablespoons of rum or whisky

Preparation

1)Wash the Aloe vera leaf (or leaves) and remove the thorns. Cut into pieces.
2)Put the Aloe vera pieces, the honey and whisky (or rum) in a blender or extractor.
3)Whisk for 2 to 3 minutes.

You will obtain a greenish syrup. The amount of syrup obtained by the above quantities of the three elements constitutes a "processing unit". Keep the syrup refrigerated.

Use

Before drinking the syrup, shake the bottle to thoroughly mix the components.
Take one tablespoon of this syrup three times a day: mornings, noon and night, 1/2 hour before meals.
The above preparation can last about ten days.
Don't stop taking the "processing unit" until it is totally used up (even if you get what seem to be signs of improvement).

Medical Checkup

It's very important to do medical tests to ascertain the progress (or lack thereof) of the above treatment concerning the disease.
It is specifically necessary to check before, during and after the treatment to know if the cancer still progresses, has been stabilized, diminishes, or has actually left. Only the results of such controls can determine the true state of the cancer, not the subjective feelings of improvement that might be felt by the cancer patients. In fact, it is commonly observed that this treatment quickly induces a certain sensation of well-being and improvement in the sick person. But those feelings don't constitute any proof that the cancer is truly cured. It is dangerous to let oneself be guided by any such sensations.

Duration of the Treatment

As mentioned, medical monitoring is very important. If the first "round of treatment" does not work to satisfaction, the patient must do checkups to determine where s/he is at and whether s/he must do a second (or third) round. It would be ideal to make an initial analysis of the "amount" of cancer present before beginning the treatment, and another analysis after each "processing unit" has been taken.

VERY IMPORTANT NOTE

When taking several "processing units" in a row, it is necessary to keep an interval of TEN DAYS between the taking of one unit and the following due to the Aloe Vera (sábila) plant being somewhat toxic. With these intervals of ten days, repeated ingestion of "processing units" will do no harm. For this reason, in case the recommended medical tests cannot be done, one is in no any danger (and has no reason to be fearful) when repeating the treatment (even when unnecessary), as long as the 10-day "syrup-free" interval is respected.
May be used simultaneously with conventional treatments such as chemotherapy or radiation.

After a round of treatment (or "processing unit"), one of five scenarios may apply:

1) The cancer continues growing, there is no sign of a cure.

Take another unit of treatment.

2) After two processing units have been taken, the cancer continues growing.

Double the dose, i.e. take the syrup as before in the morning, at noon and at night but this time, take two spoonfuls before each meal. Repeat this double dose until the cancer stops.

3) The cancer no longer grows and has effectively stopped: a good sign.

Take another round of a normal "processing unit". That is ... take one spoonful again, morning, noon and night, before each meal.

4) The cancer diminishes: a very good sign.

Undertake a new treatment round of ten days, and repeat it when necessary, until the cancer completely disappears.

5) The cancer has completely disappeared. Cases in which a single "processing unit" proves to be sufficient to eliminate the cancer are very frequent.

In this case, you can do two things: cease the treatment for good, or take yet another round of "processing unit".

The food you eat and avoid is of vital importance

Eat plenty of raw foods :
broccoli, sprouts, cauliflower, kale, garlic, beans, blueberries, onions, ginger, spirulina, chlorella, fresh fruits, etc.
Avoid :
dairy products, refined sugar, artificial colouring, chemicals, sweeteners, white flour, red meat, processed meat, etc.

Aloe vera honey syrup for preventative purposes

Lastly, you can take a "processing unit" even when you don't have any symptom of cancer, simply for PREVENTION."

Battling Cancer with Whiskey

Another article from our extensive and ever-growing library of articles of particular interest to both prostate cancer sufferers and prostate cancer health specialists. We want to both educate and inform, so you get only the best medical information.

Battling Cancer with WhiskeyA few scientists believe that whiskey can be 1 of the keys to preventing the Large C.
For a quite a number of years, liquor has been known not only to provide destructive intoxication and addiction upon its patrons, however as well as deterrent to a fit lifestyle. However as a potential weapon against cancer? Sounds controversial.
Rumors that only malt whiskey can be a thing to combat cancer have begun circulating recently. Whether it actually holds any water has yet to be proven. Based on data from 1 of the theory?south proponents, a consultant to the whiskey industry, Dr. Jim Swan, the antioxidants present in whiskey, particularly ellagic acid, can reduce the chance of developing cancer, since this acid fights the unstable atoms that aid in rapid cell replication. He added that the even more cells were produced, the even more likely that rogue cancer cells will be born. ?Whiskey can protect you from cancer and science proves it,? he said, speaking at the EuroMedLab 2005 conference in Glasgow. Dr Swan explained that ellagic acid, which is in greater concentration in whiskey than in red wine, breaks down the harmful free radicals present in our body.
Nevertheless, Cancer Research UK remains unconvinced. The professional has raised concerns that what Dr Swan and his supporters are pushing may mislead consumers into drinking excessive numbers of whiskey just to avoid cancer. Cancer Research noted that liquor intake can finally lead to certain kinds of cancer, like those in the esophagus, throat, mouth, bowel and liver. Dr Swan?south idea that whiskey can stop cancer also received criticism, owing mostly to an absence of population information supporting them. Contrariwise, based on data from the professional?south head of cancer information Lesley Walker, there survives evidence that high alcohol consumption does increase cancer risks. Ms Walker noted that while ellagic acid is a formidable antioxidant and might greatly aid in the fight against cancer, its presence in whiskey isn't reason enough for people to start drinking higher, especially as ellagic acid can also be observed in certain fruits.
The concept that a certain type of alcohol will help deter cancer is novel and, for frequent drinkers, even noble. What liquor patron would ignore this theory? However, however, Dr Swan?south ideas remain untested and there doesn^t exist any known positive link between whiskey and cancer. If there would be something that indicate this is true at one time or another in the forseeable future, then it will be considered revolutionary. In any case, in the absence of adequate information at present, whiskey as a deterrent to cancer is a dubious believed. While we all hope and pray that a different option coarse of action to cancer will surface soon, this is probably not the time to turn into this optimistic about whiskey?south alleged benefits.
Note: This article can be freely reproduced as long as the AUTHOR'S resource box at the bottom of this article is included and and all links must be Active/Linkable with no syntax changes.
Charlene J. Nuble 2005. For new links and information about cancer, please go to: http://cancer.besthealthlink.net/ or even for updated links and information on all health related topics, go to: http://www.besthealthlink.net/
Article source: http://www.topiccenter.com/Cancer/

Most of the articles in this part of Prostate Cancer Answers have been written by third parties, usually medical journalists and experienced cancer physicians. Whilst we make every attempt to verify the quality of information provided, we do not accept responsibility for the accuracy of articles written by such individuals.
We encourage you to report to us any article which you might consider misleading or inaccurate in any way. We will take steps to verify the article and either make appropriate corrections or remove it from this site. We want your visit to Prostate Cancer Answers to be an educational and rewarding experience.

Mesothelioma

Mesothelioma, specifically, mesothelioma, a rare form of cancer that develops from the protective lining that covers many internal organs of the body, the mesothelium. It is usually caused by exposure to asbestos.

The most frequent location is the pleura (outer layer of the lungs and internal chest wall), but can also occur in the peritoneum (the lining of the abdominal cavity), the pericardium (the sac that surrounds the heart) or tunica vaginal (a sac that surrounds the testicles).

Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles and glass, or have been exposed to asbestos dust and fibers in other ways. It was also suggested that washing the clothes of a family member who worked with asbestos or glass can put a person at risk of developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking increases the risk of other asbestos-induced cancers . Those who have been exposed to asbestos often use lawyers to claim damages for asbestos-related diseases, including mesothelioma. Compensation for asbestos funds or lawsuits is an important issue in the practice of law in mesothelioma.

Symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis can be suspected from the chest radiograph and CT scan, and confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to clear the pleural space (called pleurodesis), which prevents the accumulation of more fluid and pressing on the lung. Despite treatment with chemotherapy, radiotherapy or surgery, sometimes the disease carries a poor prognosis. Research on screening tests for early detection of mesothelioma is ongoing.

Historic usage of Asbestos

Asbestos use in human culture dates back at least 4,500 years, when evidence shows that inhabitants of the Lake Juojärvi region in East Finland strengthened earthenware pots and cooking utensils with the asbestos mineral anthophyllite.^[12] Asbestos was named by the ancient Greeks. One of the first careful descriptions of the material is attributed to Theophrastus in his text On Stones, around 300 BC, although the naming of minerals was not very consistent at that time (the modern Greek word ἀσβεστος stands for lime, not for the material known as asbestos in English). The term asbestos is traceable to Roman naturalist Pliny the Elder's manuscript Natural History, and his use of the term asbestinon, meaning "unquenchable".^[1][2][12] While Pliny is popularly attributed with recognising the detrimental effects of asbestos on slaves,^[13] examination of primary sources shows that this is not so.^[14] Charlemagne, the first Holy Roman Emperor, is said to have had a tablecloth made of asbestos.^[15]
Wealthy Persians, who bought asbestos imported over the Hindu Kush, amazed guests by cleaning the cloth by simply exposing it to fire. According to Biruni in his book of Gems, any cloths made of asbestos (Persian: آذرشست, āzarshast or Persian: آذرشب, āzarshab) were called (Persian: شستكه) shastakeh.^[16] Some of the Persians believed the fiber was fur from an animal (named samandar, Persian: سمندر) that lived in fire and died when exposed to water,^[17][18] hence the old mistaken myth that the salamander tolerated fire.
While traveling to China, Marco Polo described observing miraculous garments that were cleaned by being placed in fires. These garments were likely made from asbestos^{[citation needed]}.
Some archeologists believe that ancients made shrouds of asbestos, wherein they burned the bodies of their kings, in order to preserve only their ashes, and prevent their being mixed with those of wood or other combustible materials commonly used in funeral pyres.^[19] Others assert that the ancients used asbestos to make perpetual wicks for sepulchral or other lamps.^[17] In more recent centuries, asbestos was indeed used for this purpose. Although asbestos causes skin to itch upon contact, ancient literature indicates that it was prescribed for diseases of the skin, and particularly for the itch. It is possible that they used the term asbestos for soapstone, because the two terms have often been confused throughout history.<sup>[19]

FROM WIKIPEDIA</sup>